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Kelvin Lim, M.D.

2-170 CMRR

Dr. Lim is a Professor in the Department of Psychiatry where he holds the Drs. T.J. and Ella M. Arneson Endowed Chair. Dr. Lim received a B.A. in Human Biology and an M.D. from Johns Hopkins University. He completed an internship and residency in psychiatry at Stanford University. Following a neuroimaging fellowship at Stanford he joined the faculty at Stanford as an Assistant Professor in the Department of Psychiatry and Behavioral Sciences. In 1998 he became a research psychiatrist at the Nathan Kline Institute for Psychiatric Research, Center for Advanced Brain Imaging in Orangeburg, NY, where he also held an appointment as an Associate Professor in the New York University School of Medicine Department of Psychiatry. In 2001 he joined the University of Minnesota faculty in the Department of Psychiatry.

Research Interests:

Current projects and directions include:

  • Determining the specificity of white matter abnormalities in various neuropsychiatric disorders with known or suspected white matter involvement.
  • Determining the functional consequences of altered white matter diffusion parameters.
  • Elucidating the neurobiological underpinnings of the in vivo imaging findings
  • Supplementing our imaging data with genomic information
  • Developing additional magnetic resonance imaging methods to provide more specific information about myelin status and neuroaxonal tissue.

Selected Publications:

Alexopoulos GS, Kiosses D, Choi S, Murphy CF, Lim KO. Microanatomy of treatment response in late life depression: a preliminary study. Am J Psychiatry 2002; In press.

Lim KO, Choi S, Pomara N, Wolkin A, Rotrosen JP: Reduced Frontal White Matter Integrity in Cocaine Dependence: A Controlled Diffusion Tensor Imaging Study. Biological Psychiatry 2002; In Press.

Hoptman M, Volavka J, Johnson G, Weiss E, Bilder RM, Lim KO: Frontal white matter, aggression and impulsivity in men with schizophrenia. Biological Psychiatry 2002; In Press.

Pomara N, Crandall DT, Choi SJ, Johnson G, Lim KO, White matter abnormalities in HIV-1 infection: A diffusion tensor imaging study. Psychiatry Res 2001; 106(1):15-24.

Lim KO, Rosenbloom MJ, Faustman WO, Sullivan EV, Pfefferbaum A: Cortical gray matter deficit in patients with bipolar disorder. SchizophreniaResearch 1999; 40:219-227.

Lim KO, Hedehus M, Moseley M, deCrespigny A, Sullivan EV, Pfefferbaum A: Compromised white matter tract integrity in schizophrenia inferred from diffusion tensor imaging. Arch Gen Psychiatry 1999; 56:367-374.