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Jinjin Zhang, Ph.D.

zhan1029.jpg
Research Associate
1-211E CMRR
612-626-2001
zhan1029@umn.edu

I got my Ph.D. in physics from University of Minnesota at 2014. I mainly work on developing ultra-short TE sequences (SWIFT) and frequency modulated pulses, along with some applications.

Research Interests:

  • Development of ultra-short TE sequence and corresponding reconstruction algorithm
  • Design of frequency-modulated RF pulse
  • Relaxation time constant mappings (T1, T1rho, T2*)
  • Quanfitication of the bio-distribution of iron oxide nanoparticles at high concentration using postive contrast for nanoparticle-based cancer therapies (e.g. hyperthermia, immunotherapy)

Selected Publications:
  • N. Manuchehrabadi, Z. Gao, Jinjin Zhang, H. Ring, Q. Shao, F. Liu et al. Improved tissue cryopreservation using inductive heating of magnetic nanoparticles, Science - Translation Medicine, 2017, 9 (379) (Cover article)
  • Jinjin Zhang, H. Ring, et al. Quantification and Biodistribution of Iron Oxide Nanoparticles in the Primary Clearance Organs of Mice using T1 Contrast for Heating, Magn Reson Med, 2016
  • A. Kishimoto, Y. Kishimoto, D. Young, Jinjin Zhang, et. al, High and ultrahigh-field magnetic resonance imaging of naïve, injured, and scarred vocal fold mucosae in rats, Dis Model Mech., 2016
  • Jinjin Zhang, Michael Garwood, Jang-Yeon Park, The full analytical solution of the Bloch equation when using a hyperbolic-secant driving function, Magn Reson Med, 2016
  • K. Hurley, H. Ring, M. Etheridges, Jinjin Zhang, et. al, Predictable Heating and Positive MRI Contrast from a Mesoporous Silica-Coated Iron Oxide Nanoparticle, Molecular Pharmaceutics, 2016, 13 (7), p2172 
  • S. Daniel, S. Pailloux, Jinjin Zhang, et. al, Electrodeposited Fe and Fe–Au nanowires as MRI contrast agents, Chemical Communications, 2016, 52, 12634
  • Jinjin Zhang, Mikko Nissi, Djaudat Idiyatullin, Shalom Michaeli, Michael Garwood, Jutta Ellermann, Capturing Fast Relaxing Spins with SWIFT Adiabatic Rotating Frame Spin-lattice Relaxation (T1ρ) Mapping, NMR in Biomedicine, 29(4), p420, 2016
  • Jinjin Zhang, Djaudat Idyiatullin, Curt Corum, Naoharu Kobayashi, Michael Garwood, Gradient modulation in SWIFT. Magn Reson Med, 75(2), p537, 2016
  • Wang L, Nissi MJ, Tóth F, Shaver J, Johnson CP, Zhang Jinjin, Garwood M, Carlson CS, Ellermann JM, Multiparametric MRI of Epiphyseal Cartilage Necrosis (Osteochondrosis) with Histological Validation in a Goat Model. PLoS One, 2015. 
  • Jinjin Zhang, R. Chamberlain, M. Etheridge, D. Idyiatullin, C. Corum, J. Bischof, M. Garwood, Quantifying iron-oxide nanoparticles at high concentration based on longitudinal relaxation using a 3D SWIFT Look-Locker sequence. Magn Reson Med, 71 (6), 1982, 2014 (Cover article)
  • Etheridge, K. Hurley, Jinjin Zhang, et al. Accounting for biological aggregation in heating and imaging of magnetic nanoparticles. Technology, 2, 3, 2014
  • M. Nissi, F. Toth, Jinjin Zhang, et al. Susceptibility Weighted Imaging of Cartilage Canals in Porcine Epiphyseal Growth Cartilage ex vivo and in vivo. Magn Reson Med, 71 (6), 2097, 2013
  • F. Toth, M. Nissi, Jinjin Zhang, et al. Histological confirmation and biological significance of cartilage canals demonstrated using high field MRI in swine at predilection sites of osteochondrosis. Journal of Orthopedic Research, 31 (12), p2006, 2013
  • K. R. Hurley, Y. Lin, Jinjin Zhang, et al. Effects of Mesoporous Silica Coating and Postsynthetic Treatment on the Transverse Relaxivity of Iron Oxide Nanoparticles. ChemMater, 25 (9), 2013
  • L. Lehto, A. Sierra, C. Corum, Jinjin Zhang, et al. Detection of Calcifications In Vivo and Ex Vivo After Brain Injury in Rat Using SWIFT.NeuroImage, 61, 761, 2012
  • M. Garwood, D. Idiyatullin, C. Corum, R. Chamberlain, S. Moeller, N. Kobayashi, L. Lehto, Jinjin Zhang, et al. Capturing Signals from Fast-relaxing Spins with Frequency-Swept MRI: SWIFT. “Encycloepedia of Magnetic Resonance”. John Wiley & Sons, 2012
  • Kendi, S. Khariwala, Jinjin Zhang, et al. Transformation in Mandibular Imaging With Sweep Imaging With Fourier Transform Magnetic Resonance Imaging. Arch Otolaryngol Head and Neck Surg, 137 (9), 916, 2011

Conference talks

  • Jinjin Zhang, Hattie Ring, Michael Garwood, Djaudat Idiyatullin, Characterizing iron oxide nanoparticles using 4D spectroscopic SWIFT, 24th  annual meeting of ISMRM, Singapore, 2016

  • Jinjin Zhang, A. Petryk, R. Reeves, H. Ring, D. Idiyatullin, P. Hoopes, M. Garwood, In-vivo quantification of iron oxide nanoparticles at high concentration in a murine breast tumor model using positive contrast, The 23rd  annual meeting of ISMRM, Toronto, Canada, 2015

  • Jinjin Zhang, H. Ring, K. Hurley, Q. Shao, N. Klein, C. Haynes, J. Bischof, M. Garwood, Using SWIFT T1 mapping to quantify iron oxide nanoparticles uptake and biodistribution in organs in-vivo. The 23rd  annual meeting of ISMRM, Toronto, Canada, 2015

  • Jinjin Zhang, et al. Gradient-modulated SWIFT for SAR reduction and controlled short-T2* sensitivity, 22th annual meeting ISMRM, Milan, Italy, 2014

  • Jinjin Zhang, et al. SWIFT with magnetization preparation: Signal partitioning and 3D measurement of adiabatic T1rho. 21th annual meeting ISMRM, Salt Lake City, USA, 2013