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Multi-Band Accelerated Pulse Sequences

The multi-band accelerated EPI sequences developed at CMRR are now available for use at other institutions on compatible Siemens scanners by C2P agreement with CMRR and Siemens.

These sequences and the accompanying reconstructions are being actively developed as key components of the Human Connectome Project.

Gallery of example images & protocols

The available sequence variants and supported software versions are listed below. If you are interested in obtaining these sequences, the CMRR C2P instructions and agreement can be found on this page at the UMN Office for Technology Commercialization. Once you have executed a C2P agreement and have been given an access password, the sequence binaries can be downloaded here by selecting the desired release number.

Note to users: If you have noticed a bug or have a request for a new feature in a future release, please open a new support request. Be sure to include the sequence version number (e.g. VB17A R006a), sequence variant (e.g. BOLD, diffusion), and the model of scanner you are using in the problem description.

Security concerns: The sequences and software are developed in a firewalled environment, the web server is regularly checked for network vulnerabilities, and the downloadable files here are regularly scanned for viruses. To detect unexpected changes, the downloads available here are regularly checked remotely against baseline checksums stored on the remote machine. Also, Siemens provides virus software for their scanners. You can confirm that you have downloaded a valid version correctly by comparing a md5sum of the downloaded file with these checksums.


Download Multi-Band EPI 2D BOLD/SE/DIFF Sequences:

Development Release R011a
Released 9 June 2014
Expires 1 December 2014

Release Notes R011a

Release R011a for VB17A (build 9-Jun-2014)
Release R011a for VB19A (build 9-Jun-2014)
Release R011a for VD11D (build 9-Jun-2014)
Release R011a for VD13A-SP4 (build 9-Jun-2014)
Release R011a for VD13C-SP2 (build 9-Jun-2014)
Release R011a for VD13D (build 9-Jun-2014)

Archive Release HCP_v1
NOTE: This version is only provided for continuity for ongoing longitudinal studies started in 2012 or earlier. It has significant known issues. For new studies it is highly recommended to use the most current version. No further updates will be provided for this version.
Released 10 February 2014
Expires 1 March 2016

Release Notes HCP_v1
Release HCP_v1 for VB17A (build 3-Mar-2014)
Release HCP_v1 for VD11D (build 10-Feb-2014)


Remote Accelerated Reconstruction

An optional remote reconstruction server is available which allows for the possibility of dramatically improving the image reconstruction speed for demanding studies.

This is currently only available by special request.

A description of the setup with sample timing results is available.


Download Multi-Band EPI Remote Reconstruction Server:

Release R006
Major update, adds optional CUDA GPU support. Compatible with all sequence versions.
Released 3 May 2013
Release R006a for Linux x86-64


Relevant references:

  1. Moeller S, Yacoub E, Olman CA, Auerbach EJ, Strupp J, Harel N, et al. Multiband multislice GE-EPI at 7 tesla, with 16-fold acceleration using partial parallel imaging with application to high spatial and temporal whole-brain fMRI. Magn Reson Med 2010;63(5):1144-1153. [PubMed]

  2. Setsompop K, Gagoski BA, Polimeni JR, Witzel T, Wedeen VJ, Wald LL. Blipped-controlled aliasing in parallel imaging for simultaneous multislice echo planar imaging with reduced g-factor penalty. Magn Reson Med 2012;67(5):1210-1224. [PubMed]

  3. Xu J, Moeller S, Auerbach EJ, Strupp J, Smith SM, Feinberg DA, Yacoub E, Ugurbil K. Evaluation of slice accelerations using multiband echo planar imaging at 3T. Neuroimage 2013;83(0):991-1001. [PubMed]

  4. Auerbach EJ, Xu J, Yacoub E, Moeller S, Ugurbil K. Multiband accelerated spin-echo echo planar imaging with reduced peak RF power using time-shifted RF pulses. Magn Reson Med 2013;69:1261-1267. [PubMed]

  5. Sotiropoulos SN, Moeller S, Jbabdi S, Xu J, Andersson JL, Auerbach EJ, Yacoub E, Feinberg D, Setsompop K, Wald LL, et al. Effects of image reconstruction on fiber orientation mapping from multichannel diffusion MRI: Reducing the noise floor using SENSE. Magn Reson Med 2013;70(6):1682-1689. [PubMed]

View CMRR MB C2P July 2014 in a full screen map

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