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Christophe Lenglet, Ph.D.


Associate Professor

Institute for Translational Neuroscience Scholar (ITN)

Phone: 612-625-7576

Office: 2-128 CMRR

Email: clenglet 'at' umn.edu

Dr. Lenglet is an Assistant Professor at the Center for Magnetic Resonance Research (Department of Radiology) and a Scholar of the Institute for Translational Neuroscience (ITN). He was a 2014-2016 McKnight Land-Grant Professor. After receiving a M.Sc. in Computer Science & Engineering from the Compiègne University of Technology (Compiègne, France, 2003), and a M.Sc. in Applied Mathematics from École Normale Supérieure de Cachan (Cachan, France, 2003), he earned a Ph.D. in Biomedical Imaging and Neuroscience from INRIA Sophia Antipolis - Méditerranée (Sophia Antipolis, France, 2006). He then joined the Imaging and Visualization Department at Siemens Corporate Research in Princeton, New Jersey as a Research Scientist. In 2008, he moved to the University of Minnesota as a Research Associate in the Department of Electrical and Computer Engineering. In 2010, he became a faculty member of the Center for Magnetic Resonance Research.

Dr. Lenglet’s group develops computational tools to harness the power of high-field Magnetic Resonance Imaging (MRI) for neuroscience and clinical applications. His research aims at better understanding the structural and functional alterations of brain connections in neurodegenerative disorders. He also enjoys swimming, biking, running, and has competed in several Ironman triathlons.

On April 27, 2014, Christophe Lenglet, McKnight Land-Grant Assistant Professor, gave a thought-provoking talk at TEDxUMN http://tedxumn.com/ (See his talk at http://youtu.be/4-n3Vcd4gHo)

Research Interests:

Selected Publications:

S.N. Sotiropoulos, S. Jbabdi, J. Xu, J.L. Andersson, S. Moeller. E.J. Auerbach, M.F. Glasser, M. Hernandez, G. Sapiro, M. Jenkinson, D.A. Feinberg, E. Yacoub, C. Lenglet, D.C. Van Essen, K. Ugurbil, T.E. Behrens, Advances in diffusion MRI acquisition and processing in the Human Connectome Project, Neuroimage, S1053-8119(13):00551-X, May 2013

K. Ugurbil, J. Xu, E.J. Auerbach, S. Moeller, A. Vu, J.M. Duarte-Carvajalino, C. Lenglet, X. Wu, S. Schmitter, P-F. Van de Moortele, J. Strupp, G. Sapiro, F. De Martino, D. Wang, N. Harel, M. Garwood, L. Chen, D.A. Feinberg, S.M. Smith, K.L. Miller, S.N. Sotiropoulos, S. Jbabdi, J.L. Andersson, T.E. Behrens, M.F. Glasser, D. Van Essen, E. Yacoub, for the WU-UMinn HCP Consortium, Pushing spatial and temporal resolution for functional and diffusion MRI in the Human Connectome Project, Neuroimage, S1053-8119(13):00506-5, May 2013

J.M. Duarte-Carvajalino, G. Sapiro, N. Harel, C. Lenglet. A Framework for Linear and Nonlinear Registration of Diffusion-weighted MRIs using Angular Interpolation, Frontiers in Neuroscience, 7(41), April 2013

E. Caruyer, C. Lenglet, G. Sapiro, R. Deriche. Design of Multi-shell Sampling Schemes with Uniform Coverage in diffusion MRI, Magnetic Resonance in Medicine, 69(6):1534-40, June 2013

E. Caruyer, I. Aganj, C. Lenglet, G. Sapiro, R. Deriche. Motion detection in diffusion MRI via online ODF estimation, International Journal of Biomedical Imaging, doi:10.1155/2013/849363, January 2013

S. N. Sotiropoulos, S. Moeller, S. Jbabdi, J. Xu, J. L. Andersson, E. J. Auerbach, E. Yacoub, D. Feinberg, K. Setsompop, L. Wald, T. E. Behrens, K. Ugurbil, C. Lenglet. Effects of image reconstruction on fiber orientation mapping from multi-channel diffusion MRI: Reducing the noise floor using SENSE, Magnetic Resonance in Medicine, doi: 10.1002/mrm.24623, February 2013

L. Zhan, B.A. Mueller, N. Jahanshad, Y. Jin, C. Lenglet, E. Yacoub, G. Sapiro, K. Ugurbil, N. Harel, A. Toga, K.O. Lim, P. Thompson. MR Field Strength Effects on Diffusion Measures and Brain Connectivity Networks, Brain Connectivity, 3(1):72-86, January 2013

J.M. Duarte-Carvajalino, N. Jahanshad, C. Lenglet, K.L. McMahon, G.I. de Zubicaray, N.G. Martin, M. Wright, P.M. Thompson, G. Sapiro. Hierarchical Topological Network Analysis of Anatomical Human Brain Connectivity and Differences Related to Sex and Kinship, Neuroimage, 59(4), 3784-3804, February 2012

C. Lenglet, A. Abosch, E. Yacoub, G. Sapiro, N. Harel. Comprehensive in vivo Mapping of the Human Basal Ganglia and Thalamic Connectome in Individuals using 7T MRI, PLoS ONE, 7(1): e29153, January 2012

I. Aganj, C. Lenglet, G. Sapiro, E. Yacoub, K. Ugurbil, N. Harel. Reconstruction of the Orientation Distribution Function in Single and Multiple Shell Q-Ball Imaging within Constant Solid Angle, Magnetic Resonance in Medicine, 64(2), 554-566, June 2010 (3rd most cited MRM paper in 2010).

H.E. Cetingul, L. Dumont, M. Nadar, P. Thompson, G. Sapiro, and C. Lenglet, Importance Sampling Spherical Harmonics to Improve Filtered Probabilistic Tractography, International Workshop on Pattern Recognition in Neuroimaging (PRNI'13), Philadelphia, PA, USA, June 22-24 (Talk)

H.E. Cetingul, L. Dumont, M. Nadar, P. Thompson, G. Sapiro, and C. Lenglet, Simultaneous ODF estimation and robust probabilistic tractography from HARDI, Computational Diffusion MRI (CDMRI'12) Workshop at MICCAI 2012, Nice, France, October 2012 (Talk)

A. Kamath, I. Aganj, J. Xu, E. Yacoub, K. Ugurbil, G. Sapiro, C. Lenglet, Generalized Constant Solid Angle ODF and Optimal Acquisition Protocol for Fiber Orientation Mapping, Computational Diffusion MRI (CDMRI'12) Workshop at MICCAI 2012, Nice, France, October 2012 (Talk)

J. M. Duarte-Carvajalino, C. Lenglet, K. Ugurbil, S. Moeller, L. Carin, C. Sapiro, A Framework for Multi-task Bayesian Compressive Sensing of Diffusion Weighted MRI, Computational Diffusion MRI (CDMRI'12) Workshop at MICCAI 2012, Nice, France, October 2012