Faculty and Staff

You are here

Essa Yacoub

1-211K CMRR

Research Interests:

My research interests are in developing and applying high field magnetic resonance imaging (MRI) and functional MRI (fMRI) for human applications. My work has emphasized pushing the spatial and temporal resolution limits of fMRI using high magnetic fields and MRI pulse sequence developments. With the ability to non-invasively monitor the working human brain with such high degrees of spatial and temporal precision, the aim is to map and understand intrinsic functional architectures and neuronal inter-connections.

Selected Publications:

Yacoub E, Shmuel A, Pfeuffer J, Moortele P-F, Adriany G, Andersen P, Vaughan J.T., Merkle H, Ugurbil K, Hu X. “Imaging Brain Function in Humans at 7 Tesla”, Magn Reson Med (2001); 45: 588-594.

Yacoub E, Duong T, van de Moortele P.-F., Lindquist M, Adriany G, Kim S.-G., Ugurbil K, Hu X. “Spin-Echo fMRI in Humans using High Spatial Resolutions and High Magnetic Fields”, Magn Reson Med (2003); 49: 655-664.

Yacoub E, Shmuel A, Logothetis N, Ugurbil K. “Robust detection of ocular dominance columns in humans using HSE BOLD at 7 Tesla”, NeuroImage (2007); 37 (4): 1161-1177.

Yacoub E, Harel N, Ugurbil K. “High-field fMRI unveils orientation columns in humans”, Proc Natl Acad Sci U S A (2008);105(30):10607-10612.

Feinberg DA, Moeller S, Smith SM, Auerbach E, Ramanna S, Gunther M, Glasser MF, Miller KL, Ugurbil K, Yacoub E. Multiplexed echo planar imaging for sub-second whole brain FMRI and fast diffusion imaging. PLoS One. 2010 Dec 20;5(12):e15710.

De Martino, F., Esposito, F., van de Moortele, P.F., Harel, N., Formisano, E., Goebel, R., Ugurbil, K., Yacoub, E., 2011. Whole brain high-resolution functional imaging at ultra high magnetic fields: an application to the analysis of resting state networks. Neuroimage 57, 1031-1044.

Zimmermann J, Goebel R, De Martino F, van de Moortele PF, Feinberg D, Adriany G, Chaimow D, Shmuel A, U─čurbil K, Yacoub E. Mapping the organization of axis of motion selective features in human area MT using high-field fMRI. PLoS One. 2011;6(12):e28716.

Olman CA, Harel N, Feinberg DA, He S, Zhang P, Ugurbil K, Yacoub E. Layer-specific fMRI reflects different neuronal computations at different depths in human V1. PLoS One. 2012;7(3):e32536.

Van Essen DC, Ugurbil K, Auerbach E, Barch D, Behrens TE, Bucholz R, Chang A, Chen L, Corbetta M, Curtiss SW, Della Penna S, Feinberg D, Glasser MF, Harel N, Heath AC, Larson-Prior L, Marcus D, Michalareas G, Moeller S, Oostenveld R, Petersen SE, Prior F, Schlaggar BL, Smith SM, Snyder AZ, Xu J, Yacoub E. The Human Connectome Project: a data acquisition perspective. Neuroimage. 2012 Oct 1;62(4):2222-31.

Hu, X., Yacoub, E., 2012. The story of the initial dip in fMRI. Neuroimage 62(2): 1103-1108.Neuroimage. 2013 Oct 15;80:80-104.

Ugurbil, K., Xu, J., Auerbach, E.J., Moeller, S., Vu, A., Duarte-Carvajalino, J.M., Lenglet, C., Wu, X., Schmitter, S., Van de Moortele, P.F., Strupp, J., Sapiro, G., De Martino, F., Wang, D., Harel, N., Garwood, M., Chen, L., Feinberg, D.A., Smith, S.M., Miller, K.L., Sotiropoulos, S.N., Jbabdi, S., Andersson, J.L., Behrens, T.E., Glasser, M.F., Van Essen, D., Yacoub, E., 2013. Pushing spatial and temporal resolution for functional and diffusion MRI in the Human Connectome Project. Neuroimage 80: 80-104

Warren, S.G., Yacoub, E., Ghose, G.M., 2014. Featural and temporal attention selectively enhance task-appropriate representations in human primary visual cortex. Nat Commun 5, 5643

De Martino, F., Moerel, M., Ugurbil, K., Formisano, E., Yacoub, E., 2015. Less noise, more activation: Multiband acquisition schemes for auditory functional MRI. Magn Reson Med 74, 462-467.

Kemper, V.G., De Martino, F., Vu, A.T., Poser, B.A., Feinberg, D.A., Goebel, R., Yacoub, E., 2015. Sub-millimeter T2 weighted fMRI at 7 T: comparison of 3D-GRASE and 2D SE-EPI. Front Neurosci 9, 163

Muckli, L., De Martino, F., Vizioli, L., Petro, L.S., Smith, F.W., Ugurbil, K., Goebel, R., Yacoub, E., 2015. Contextual Feedback to Superficial Layers of V1. Curr Biol 25, 2690-2695