Multi-Band Accelerated EPI Pulse Sequences

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The multi-band accelerated EPI sequences developed at CMRR are now available for use at other institutions on compatible Siemens scanners by C2P agreement with CMRR and Siemens.

These sequences and the accompanying reconstructions are being actively developed as key components of the Human Connectome Project.

Gallery of example images & protocols

The available sequence variants and supported software versions are listed below. If you are interested in obtaining these sequences, the CMRR C2P instructions and agreement can be found on the web page of the University of Minnesota Office for Technology Commercialization. Once you have executed a C2P agreement and have been given an access password, the sequence binaries can be downloaded here by selecting the desired release number.

Note to users: If you have noticed a bug or have a request for a new feature in a future release, please open a new support request. Be sure to include the sequence version number (e.g. VB17A R006a), sequence variant (e.g. BOLD, diffusion), and the model of scanner you are using in the problem description.

Security concerns: The sequences and software are developed in a firewalled environment, the web server is regularly checked for network vulnerabilities, and the downloadable files here are regularly scanned for viruses. To detect unexpected changes, the downloads available here are regularly checked remotely against baseline checksums stored on the remote machine. Also, Siemens provides virus software for their scanners. You can confirm that you have downloaded a valid version correctly by comparing a md5sum of the downloaded file with these checksums.

Download Multi-Band EPI 2D BOLD/SE/DIFF Sequences:

Release R015
Released 3 March 2017
Expires 6 December 2017

Release Notes R015a
Release R015a for VB17A (build 20-Apr-2017)
Release R015a for VB17A-UHF (UHF systems w/ GPU) (build 20-Apr-2017)
Release R015 for VB17A-Step2.3/F37 (8Tx/16Tx F37-F40) (build 6-Mar-2017)
Release R015 for VB19A (build 5-Mar-2017)
Release R015 for VB20P (build 6-Mar-2017)
Release R015 for VD11D (build 3-Mar-2017)
Release R015a for VD13A (SP4 and newer) (build 18-Jul-2017)
Release R015a for VD13B (build 11-Apr-2017)
Release R015 for VD13C-SP2 (build 6-Mar-2017)
Release R015a for VD13D (build 18-Jul-2017)
Release R015a for VE11A (build 18-Jul-2017)
Release R015a for VE11B (build 18-Jul-2017)
Release R015a for VE11C (build 19-Apr-2017)
Release R015a for VE11P (build 20-Jun-2017)
Release R015a for VE11R (build 10-Jul-2017)

Download Multi-Band EPI Remote Reconstruction Server:

An optional remote reconstruction server is available which allows for the possibility of dramatically improving the image reconstruction speed for demanding studies.

This is currently only available by special request.

A description of the setup with sample timing results is available.

Release R008
Updated to support sequence versions R014 and newer.
Released 3 August 2016
Release R008 for Linux x86-64


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  2. Setsompop K, Gagoski BA, Polimeni JR, Witzel T, Wedeen VJ, Wald LL. Blipped-controlled aliasing in parallel imaging for simultaneous multislice echo planar imaging with reduced g-factor penalty. Magn Reson Med. 2012;67(5):1210-1224. [PubMed]

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  5. Sotiropoulos SN, Moeller S, Jbabdi S, Xu J, Andersson JL, Auerbach EJ, Yacoub E, Feinberg D, Setsompop K, Wald LL, Behrens TEJ, Uğurbil K, Lenglet C. Effects of image reconstruction on fiber orientation mapping from multichannel diffusion MRI: Reducing the noise floor using SENSE. Magn Reson Med. 2013;70(6):1682-1689. [PubMed]

  6. Cauley SF, Polimeni JR, Bhat H, Wald LL, Setsompop K. Interslice leakage artifact reduction technique for simultaneous multislice acquisitions. Magn Reson Med. 2014 Jul;72(1):93-102. [PubMed]

  7. Setsompop K, Cohen-Adad J, Gagoski BA, Raij T, Yendiki A, Keil B, Wedeen VJ, Wald LL. Improving diffusion MRI using simultaneous multi-slice echo planar imaging. Neuroimage. 2012 Oct 15;63(1):569-80. [PubMed]

View CMRR MB C2P July 2015 in a full screen map